I think the main antagonist is really Nyxly
Supergirl vs. the Slum Lord?
Kinda low hanging fruit, isn't it? I mean I get it, they tackled most of the A-list social justice material early on, but isn't this a bit cliche . . . even for the CW? For that matter, didn't Black Lightning already do this? Or course, Supergirl'stechnically been cancelled, they probably feel like any decent writing (something they TOTALLY usedto do?) would be like fixing the front porch the week before you move.